I would imagine that as a starting point, for small changes that are less than doubling or halving, you could probably go with something like a 25-50% change in exposure time alone.
The tricky part that I found printing at 100 or 250 micron layer height on the Titan 1 is that longer cure times will also result in each layer sticking more firmly to the vat. That means that if you significantly alter the layer thickness, you may find that you need to change the lift settings and potentially lift higher or more slowly. “May” in that the amount of the increased separation force varies depending on the surface area of the part you are printing. I print a lot of large surface area parts with perpendicular orientation and no supports, that generally requires quite a lot of settings tweaking and is impacted a lot by changes to separation force. More traditional orientation to minimize per-layer surface area would be less sensitive to this.